Effect of biodegradation on PLA/graphene-nanoplatelets composites mechanical properties and biocompatibility

نویسندگان

  • Artur M. Pinto
  • Carolina Gonçalves
  • Inês C. Gonçalves
  • Fernão D. Magalhães
  • Roberto Frias
چکیده

Two types of graphene-nanoplatelets (GNP-M and GNP-C) were incorporated in PLA (poly(lactic acid)) by melt blending. Materials were biodegraded during 6 months and characterized by XRD, tensile tests, DMA and biocompatibility assays. For both fillers, low loadings (0.25 wt.%) improved mechanical properties and decreased their decay until 6 months biodegradation. PLA degradation decreased its toughness (AUC) by 10 fold, while for PLA/GNP-M and C after 6 months degradation, toughness was only reduced by 3.3 and 1.7 fold, respectively. Comparing with PLA, PLA/GNP-M and C composites presented similar (HFF-1) fibroblasts adhesion and proliferation at the surface and did not released toxic products (6 months).

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تاریخ انتشار 2014